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The algorithm, with the name of fuzzy alignment algorithm (FAA), extends Marques' algorithm to affine transformations.
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BLASTn was used because of its ability to find "fuzzy" alignments to related nucleotide sequences from other organisms.
Other programs that allow for fuzzy alignments to mimic hybridization conditions, such as GCG's findpatterns or EMBOSS's fuzznuc do not scale well with 200000 probes at the genome level.
Nandakumar [45] applies a binary fixed-length minutiae representation obtained by quantizing the Fourier phase spectrum of a minutia set in a fuzzy commitment scheme, where alignment is achieved through focal point of high curvature regions.
For a few subfamilies, some hits were restricted to a short alignment region with fuzzy limits.
In our 3D ligand-based virtual screening approach called SQUIRREL, we combine shape-based rigid body alignment [2] with fuzzy pharmacophore scoring [3].
Several other approaches have been proposed to improve the alignment within fingerprint-based fuzzy vaults [59 61].
Large-scale automatic annotation of gene function is limited by local alignments' incomplete motif matches and fuzzy domain boundaries (Kann et al., 2007).
This reflects partly the fuzzy classification boundaries of SCOP, and partly the quality of the (sub-optimal) alignments of domain pairs generated by popular alignment methods.
This intelligent method utilizes a custom fuzzy logic algorithm to control the motion of the tip electrode and automate tip/substrate alignment.
Likewise, a word differs from a motif, in that motifs are often fuzzy (meaning tolerant to substitution) and are best viewed in the context of an alignment of related sequences.
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