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Pending regulatory approval, Ra may represent a unique and distinct option for an important subgroup of patients with mCRPC; future trials should address its use in combination or in sequence with existing and novel agents.
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Ongoing randomised trials should address this issue.
Therefore, future trials should specifically address whether the combination of NT-proBNP and GDF-15 for the diagnosis of HFnEF really gives incremental value or whether one of the two markers can be used in isolation.
This review discusses important and clinically relevant outcomes that future trials should be powered to address and identifies the challenges facing the neonatal clinical trials community.
Methodological issues to be addressed in future trials should include clinically relevant relapse criteria.
Future trials should include these important outcomes.
The clinical impact of serum phosphorous reduction on the relevant outcome is far from being established, especially in light of the recently published results of the EVOLVE trial [ 2], and future studies should address whether high-bone turnover attenuation increases survival among CKD-5D subjects.
Results from the burden analysis presented here should be interpreted cautiously in light of the lack of country-specific norms used for comparison of trial patients' SF-12v2 scores, and future research should address this issue.
Future research should address this aspect in randomized clinical trials.
Future studies should address the paucity of research examining female participants as well as the lack of randomised control or crossover trials incorporating a 'true' resting control.
Future work should address response quantification.
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CEO of Professional Science Editing for Scientists @ prosciediting.com