Exact(35)
Furthermore, the in vivo pharmacodynamics characteristics were evaluated for future clinical development.
"Her initial work was to organize all the issues related to future clinical development programs".
The ability to molecularly select patients likely to respond to an investigational agent argues that future clinical development of targeted agents should be re-evaluated.
As far as Os in children is concerned, it appears to have an even more important role since the presence of Os in a child presenting as suffering of TTH results to be a prognostic marker of the future clinical development of MO[2].
However, these data collectively support future clinical development of AR-42 in the treatment of lymphoid malignancies.
It is hoped that this will lead to achieving the appropriate balance between vaccine immunogenicity and reactogenicity in future clinical development of this promising malaria vaccine candidate.
Similar(25)
We conclude that information gathered so far on these four biomarkers— sTREM-1, suPAR, proADM, and presepsin suggest that they may have a role in future clinical developments, whether as diagnostic tests, or for stratification of patients by type of insult or severity, or to assess the therapeutic activity and efficacy and during follow-up of patients.
These studies have not yet been translated into a clinical trial, but should provide the foundation for future clinical developments.
This information could promote a better understanding of their pharmacological properties as well as enabling optimal clinical use in the framework of the currently approved therapeutic schedules and in the context of future clinical developments.
However, because of low bioavailability of rapamycin, it was given constantly (in drinking water) without interruptions, whereas intermittent schedules may be more appropriate for future clinical developments as cancer-preventive interventions.
The educational strategy also serves as a model to inform the process of future clinical guideline development.
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