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Furthermore, since these experiments could not be performed in the presence of a blocker of autophagosomal/lysosomal fusion, the changes in autophagic flux at the level of synthesis are much more difficult to detect outside of organs which show a strong physiological response to brief periods of starvation.
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Since melting point is a thermodynamic process where the free energy of transition is equal to zero, the value is determined by the ratio of change in the enthalpy of fusion over the change in the entropy of fusion.
One year post fusion the mean change in ODI was −25 (95% CI −28 to −22) in females and −17 (95% CI −21 to −13) in males.
A fusion causes the change of the physical genomic position therefore loss of the regulatory elements of this gene.
Altogether, these data argue that the modulation of endosome fusion, reflected by the changes in endosome number and size, is a general property of growth factors.
The fusion might change the actual conformation of the bait and/or prey and consequently alter functionalities.
Upon administration of 4-OHT, the ER domain of the CreER fusion protein changes conformation, prompting the translocation of the fusion protein into the nucleus where the recombinase can delete DNA sequences flanked by loxP sites.
To examine whether the mitochondrial fragmentation induced by shYme1L is due to the deficiency of mitochondrial fusion, we checked the change of protein level of the mitochondrial fusion key proteins by western blot analysis.
Posterior lumbar interbody fusion (PLIF) using harvested local bone inserted into a polyetheretherketone (PEEK) cage is a commonly used procedure, but the accurate fusion rate of a cage, cage to bone contact area ratio, and the changes in fusion rate with time after surgery are unknown.
To determine whether surface area (membrane) or volume was conserved during LD fusion, we analysed the change in volume and surface area of resulting fused LDs relative to the two donor LDs.
If an additional, instrumented dorsal fusion is performed, the change of developing a post-surgical kyphosis is nearly zero[ 9].
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