For this purpose, dynamics in adhesive and fusion properties, molecular composition and architecture of the sperm plasma membrane, as well as membrane derived signalling are reviewed.
The present studies were conducted to determine how the additional α-helical regions of the peripherin/rds C-terminus affect complex formation with rom-1, glycosylation, intracellular localization and membrane fusion properties.
Such properties include, but are not limited to, solubility, dissolution, bioavailability, hygroscopicity, hydrate/solvate formation, crystal morphology, fusion properties, chemical and thermal stabilities, and mechanical properties.
These data suggest that gentamicin inhibition of endosomal fusion in the renal proximal tubule is a damage mechanism mediated by specific peptide sequences in the cytosolic tail of the giant gentamicin-binding receptor megalin and that receptors can effect the fusion properties of membranes in which they reside.
Both viruses caused a similar CPE in BHK-21 cells, characterized by rounding, aggregation and fusion properties.
Alternatively, mutations at E2-211 might affect the stability of the E2-E1 heterodimers, which would differentially affect fusion properties of the CHIKV with E1-226A E1-226V26V.
In the same study it was speculated that this change could influence the fusion properties of the HA molecule and thus may affect the pathogenicity of the virus [6].
This drug delivery system, thanks to its both magnetic and high efficient fusion properties, can be used to specifically drive the drug or pro-drug at target organ or tissue and release the therapeutic compound directly inside the target cells thus improving the efficiency and efficacy of therapy.
mfGFP was fused to several membrane proteins to evaluate its fusion properties: clathrin light chain A (CLCA), a 30 kDa component of clathrin coated pits [11] (Fig. 2B), calnexin, a 90 kDa endoplasmic reticulum (ER) chaperon protein [12] (Fig. 2C), and ryanodine receptor type 1 (RyR1), a large homotetrameric Ca2+ release channel protein in the ER [13] (Fig. 2D).
Biophysical studies have shown that saposin C has membrane fusion properties (16, 17).
