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Therefore, we do not think Rab23 fusion confers ciliary localization on receptors by simple tethering.
EML4-ALK fusion confers a characteristic histology and is detected more frequently in never or light smokers and younger patients.
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Contrary to ThiS fusion, MoaD fusion conferred a complete protection of the murine ribonuclease inhibitor (mRI) from intracellular degradation.
However, even after adjusting for age and clinicopathological factors, there was some evidence that samples with multiple copies of the fusion conferred worse survival than those with no fusion or single copies of the gene fusion.
Studies have shown that posterior laminectomy and fusions confer the greatest risk of C5 palsy.
A third issue is whether ALL-1 fusions confer resistance to apoptosis.
Several studies have indicated that TMPRSS2 ERG fusions confer a worse prognosis (Nam et al, 2007; Attard et al, 2008a; Clark et al, 2008), whereas others have not (Gopalan et al, 2009).
The envelope gene encodes an envelope protein, which induces membrane fusion, and confers protective immune responses by eliciting neutralizing, antifusion and replication-enhancing antibodies [ 17].
In thyroid adenocarcinomas the PAX8/PPAR-γ (peroxisome proliferator-activator receptor gamma 1) fusion protein confers many oncogenic properties, including increased proliferation, decreased apoptosis and the inhibition of wild-type PPAR-γ [ 7, 36- 38].
51 As a result of juxtaposing the breakpoint cluster region (BCR) promoter with the coding region of the ABL gene, the hyperactive BCR-ABL fusion protein confers myeloproliferative properties and leads to leukemogenesis.
Here, the effects of constitutively active CD40 in DCs on atherosclerosis were examined using low-density lipoprotein-deficient (Ldlr−/−) bone marrow chimeras that express a transgene containing an engineered latent membrane protein 1 (LMP)/CD40 fusion protein conferring constitutive CD40 signaling under control of the DC-specific CD11c promoter (DC-LMP1/CD40).
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