Sentence examples for fusion activity from inspiring English sources

Fusion activity can also be activated by truncation of the gp41 cytoplasmic tail, suggesting that an interaction between uncleaved Gag and the gp41 cytoplasmic tail locks Env in a non-fusogenic conformation.

All the molecules showed anti-HIV-1 fusion activity.

Lee, J. et al. Structure of the Ebola virus envelope protein MPER/TM domain and its interaction with the fusion loop explains their fusion activity.

The peptide-based drug Enfuvirtide1 is precedent that antagonists of this fusion activity may act as anti HIV-agents.

A series of new hairpin duplexes were tested for anti-HIV-1 cell cell membrane fusion activity.

Knock-down of calnexin lead to reduced fusion activity of HIV-1 envelope and reduced virion infectivity, as well as to defective cholesterol efflux, which is mediated by ABCA1.

However, purified and reconstituted human ATL1 exhibited no in vitro fusion activity.

Thus, human ATL1 is expected to exhibit fusion activity in vitro, just like Drosophila ATL.

Subsequent site-directed mutagenesis indicated that the cytoplasmic domain truncation was responsible for the enhanced fusion activity.

(B) Fusion activity of JEV SA14-14-2 and reviruses viruses measured by the fusion index in BHK21 cells.

To compare the membrane fusion activity of full-length ATLs, we used a previously established in vitro lipid-mixing assay.