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Furthermore, until now, none of the reported small-molecule MCL-1 inhibitors bound to their target with high affinity.
Furthermore, until now, none of the IGS analysis center has reported ambiguity resolution for GLONASS long baselines in their routine GNSS data processing.
Furthermore, until now, several anti-microRNA oligonucleotides with some modifications, such as 2'-O-methyl-substituted RNA oligonucleotides and mixed locked nucleic acid-DNA, have been presumed to be novel diagnostic and therapeutic agents [51].
Furthermore, until now there have been only limited data available for comparison of these two osmotic agents in a clinical setting.
Furthermore, until now, it has been difficult to evaluate mutational heterogeneity within and among tumors in a single patient because of the need for multiple tumor biopsies.
Furthermore, until now, little is known about the relationships between persistent MUPS in general practice on the one hand, and coping, social support, trust in health care, and the quality of GP-care on the other hand.
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Furthermore, and until now, in ordinary secondary care in Kinshasa, renal complications are assessed only by serum creatinine alone instead of resorting to formula -based estimates of creatinine clearance or eGFR.
Furthermore, it is, up until now, puzzling why Physcomitrella is able to integrate ectopic DNA into the genome by homologous recombination with an extraordinarily high rate [ 23, 24] so far only found in bacteria and yeast, but in no other plant or any animal.
Furthermore, we make clearer that, until now, immuno-ecologists have been thinking in terms of maternal investments in antimicrobial activity of eggs.
In the same way, a WHO Expert Consultation Group [ 27] has pointed out as limitation for the clinical usefulness of the construct MS the dichotomization of its diagnosis and the risk factors to define MS. Furthermore, the summative scales proposed until now assume that each factor has associated the same risk, and there is no evidence to support this assumption.
Furthermore, results point out that the shuffled decoding, until now never considered in hardware implementation, improves the efficiency of very high-throughput low-latency implementations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com