Furthermore, the highest levels of lymphocyte proliferation response, IL-4, IL-12 and IFN-γ production were induced following priming with the DNA vaccine and boosting with the rgD protein.
Furthermore, the highest levels of BiP and DNAJB1 were present in B35-positive lcSSc-PAH samples (BiP, p < 0.05 lcSSc-PAH B35+ vs lcSSc-PAH B35-; DNAJB1 p < 0.005 lcSSc-PAH B35+ vs lcSSc-PAH B35-) (Fig. 1, lower panel).
Furthermore, the high level of polyphenols confer apples relevant nutraceutical properties.
Furthermore, the high level of reproductibility that can now be achieved across laboratories opens up further its potential in clinical investigation (genetic and cancer, for example).
Furthermore, the high level of organic matter and alkaline condition in soil decreased their availability in plant soil system.
Furthermore, the higher level of sedation and the neuromuscular block which could decrease the lung volume did not affect the validity of the two tests.
Furthermore, the high level of noise present in the PET images, coupled with possible residual motion artefacts and attenuation artefacts [10], might complicate the perfect alignment of the two datasets and therefore increase the chances to introduce additional, anatomy-driven artefacts in the PVC-PET reconstructions.
Furthermore, the high level of genetic variability of the virus and its escape from the neutralizing antibody response are well documented and have further discouraged the HIV-1 vaccine field from considering the induction of humoral immunity as a pre-requisite for an effective HIV-1 vaccine [13], [14].
Furthermore, the high level of ROS could induce apoptotic cell death by mitochondrial apoptotic pathways [ 54].
Furthermore, the higher level of paternal education was negatively associated with the presence of asthma (P = 0.010).
