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Furthermore, manipulation of the CUL3 KLHL12 ubiquitination pathway might be used to increase collagen secretion from cells for applications in stem-cell culture, for growth of tissue components in regenerative medicine, or perhaps for ameliorating age-related degeneration of connective tissue.
Furthermore, manipulation of Plk3 had a profound effect on microtubule dynamics [9].
Furthermore, manipulation of the level of pbx2 expression in zebrafish embryos resulted in a change in the timing of the onset of shh expression in pectoral fin primordia in a low percentage of embryos (see Fig. S4 and S6).
Furthermore, manipulation in the side chain of ssHHT may provide second-generation analogues that may have a broader or different spectrum of activity.
Furthermore, manipulation of endogenous secretion, physiological replacement and supra-physiological treatment (pharmacological dosing) of these hormones are likely to be novel therapeutic targets in this group.
Furthermore, manipulation of TGF-β-induced signalling molecules (for example, c-Ski) may also promote reversal of the myofibroblast phenotype [ 45].
Similar(53)
Furthermore, manipulations of cholinergic input in the VTA can change cocaine taking.
Furthermore, manipulations of the selection of content seen by Facebook users led to their emotions moving in the predicted direction [63].
Furthermore, manipulations on some other important kinases and phosphatases are consistent with experimental observations.
Furthermore, manipulations of p53 in Drosophila life span studies have primarily been concerned with the effects of reducing p53 function using DN p53 alleles [ 9, 11, 12].
Furthermore, manipulations of growth rates in the wild using growth hormone implants have been shown to cause increased movement activity (Sundt-Hansen et al. 2009), and this may cause increased predation mortality due to greater predator exposure (Lankford et al. 2001; Biro et al. 2004; Stoks et al. 2005).
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