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The resulting reduction in renal oxygen availability is furthermore exacerbated by extra-cellular matrix (ECM) expansion, which limits oxygen diffusion, and by renal anemia [ 1, 2].
The complexity of the problem is furthermore exacerbated by the different level of the functional annotation coverage in different organisms, thus making very difficult the effective transfer of the available functional knowledge from one organism to another.
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The higher heart rates of exercise, furthermore, exacerbate the ventricular imbalance by increasing the fluid extravasation each minute [24].
Furthermore, LY294002 exacerbated PAN-induced apoptosis.
Furthermore, TCDD exacerbates the TNF-mediated inflammatory responses to LPS in vivo [ 66].
Furthermore, anemia exacerbates secondary injury among rats with a TBI by enlarging cerebral contusional areas and enhancing apoptosis [ 22].
Furthermore, HIV exacerbates HSV disease in a reciprocal fashion; symptomatic reactivations and mucocutaneous shedding of HSV are greater in frequency and quantity in HIV-infected persons.
Furthermore, it is exacerbated when the sample size is much smaller than the dimension of the random field.
Furthermore this is exacerbated by reduced antioxidant defenses.
The Purkinje system has previously been shown to play an important role in the initiation of polymorphic VT after myocardial infarction (25), and furthermore flecainide, which exacerbated the conduction block and repolarization heterogeneities in our recordings, is known to have a significant effect on the Purkinje system.
Furthermore, following vaccination, exacerbated reaction to natural or experimental infection, although uncommon, has been described in calves [ 8, 9], and resembles that previously observed in children immunized with an inactivated vaccine against the genetically and antigenically closely related pneumovirus, human RSV (HRSV) [ 10].
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