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Crosslinking of the antibody with Fcγ-receptors increased the cytotoxic potential further, without compromising its selectivity.
Thus, adult gliomas can validly be categorized broadly as GBM versus non-GBM based on pathology report diagnoses (which are utilized by SEER cancer registries), but non-GBM cannot be sub-divided further without compromising validity.
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This steel possesses excellent mechanical properties and the ductility can be further improved without compromising strength because the refined microstructure contains martensite, retained austenite and deformation-induced ferrite.
However, there remains considerable variation between hospitals in blood reduction, and national audits of blood components in the UK and elsewhere suggest that overall blood usage could be further reduced without compromising patient safety.
3 4 However, there remains considerable variation between hospitals in blood reduction in the UK 5 and elsewhere, 6 suggesting that overall blood usage could be further reduced without compromising patient safety.
Although the clinical trial evidence is not examined in this review, if necessary, a diuretic can be added to the amlodipine/valsartan combination to further reduce BP, without compromising safety and tolerability [ 64, 65].
7 Physicians can use these models as a strategy to enhance the efficiency of the diagnostic process by precluding those patients with a low probability of pulmonary embolism from further diagnostic tests, without compromising on safety (that is, missing cases of pulmonary embolism).
While the case of HIV provides a precedent for expanding access to investigational treatments to some extent, many would welcome ways to widen access even further without also compromising on research evidence (National Academy of Sciences 1991).
In order to further optimize our realtime ultrasound guided BPT protocol, we tested the hypothesis, whether exchanging the ETT with a laryngeal mask airway (LMA) prior to the procedure can further advance this technique without compromising already established patient safety features.
In the early part of the last decade, a group of researchers at NSA developed a program called THINTHREAD that had the ability to sort through the mass of data NSA receives and pick out items requiring further attention -- all without compromising the Fourth Amendment rights of Americans.
We tested the hypothesis that, by applying goal-orientated ventilation based on iterative computer simulation, VT can be reduced at high RR and much further reduced during ASPIDS, without compromising gas exchange or causing high airway pressure.
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