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To elucidate this further we searched for the previously described motifs [ 39], namely, CxxCHxxCxxC and CxxCxxxCxxC.
To investigate these DE genes further, we searched for stress-responsive cis-acting promoter elements by scanning 1000bp upstream of orthologous genes.
Taking it a step further, we searched the human genome for purine-rich elements between the -3 and -10 positions of the 3′ splice sites of annotated introns.
Further, we searched for insect PsGEF orthologs in the genomes of Nematostella vectensis (sea anemone, cnidaria), Strongylocentrotus purpuratus (sea urchin), Ciona intestinalis (sea squirt), Lottia gigantea (limpet, lophotrochozoa), and Caenorhabditis elegans.
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In a further step, we searched for identical multilocus genotypes because of clonal reproduction by stolons.
Further, we purposively searched targeted journals, including Functions of Language, Functional Linguistics, Languages in Contrast, Linguistics and the Human Sciences, Language Sciences, Language Typology, and Studies in Language.
Further, we hand-searched the Journal of Clinical Microbiology, a high-yield journal for this review topic.
Further we hand-searched references of systematic reviews until April 2012 for additional studies.
To further assess our approach we searched the literature for point mutations that pass our criteria and have experimentally determined binding affinities.
To further investigate LHP1 regulation, we searched for LHP1-Interacting Factors (LIF).
We searched further into the biological process category, and the results of the functional annotation are presented in Figure 10B D.
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