The network with the best performance was selected for further validation testing in test set 2. The AUC based on performance in test set 2 was computed, and sensitivity and specificity were determined.
Further validation testing with qualitative studies involving other stakeholders would be helpful to overcome this limitation.
As a further validation test, it was important to test the microfluidic device with a microdialysis probe in vitro.
In addition, these yield-related QTLs identified in the TE could be directly used to develop high-yielding rice lines suitable for rainfed rice ecosystems, without further validation or testing.
However, most reports on individual biomarkers and multiple biomarker panels have been only preliminary and require further validation before testing at the clinical level.
Upon further validation, this test could be used to complement currently available disease activity measures and improve patient care and outcomes.
We decided that we would include all 28 symptom domains that were mentioned regardless of frequency in the focus groups as our further validation and testing would identify those symptoms most frequent and responsive in the experience of UC.
From further validation and testing of hypotheses generated from these reconstruction efforts we expect to arrive at a conserved set of metabolic reactions that interdigitate with those of the host cell and might thus provide novel targets for therapeutic intervention.
A focus on studies supporting predictive validity would be enormously helpful in further validation of the tests' construct validity.
