Sentence examples for further trafficking of from inspiring English sources
Taken together, these data generated with the hIPΔ312 and hIPΔ307 suggests that while the C-tail is not essential for Rab5a interaction, it appears to have a role in regulating further trafficking of the hIP from the Rab5-early endosomes, perhaps to other Rab-containing transport vesicles, preventing it from recycling to the plasma membrane in a dysregulated manner.
More MAPT would accumulate, leading to further "hyperbound" MAPT and still further trafficking blocks, inducing a downward spiral of impaired microtubule trafficking and increased MAPT accumulation (Fig. 1).
Further, as trafficking of the GR and MR is regulated by FKBP51 and FKBP52, and no studies have been reported regarding the impact of PAE on these proteins, we assessed their levels in the hippocampal formation of PAE mice.
By the time he had cleared Sutil and further traffic in front of him and passed Rosberg for second place on lap 20, Webber was 27 seconds behind Vettel and the race was long over.
"Removing parking restrictions on these parts of the road could jeopardise the safety of pedestrians, cyclists and other motorists and create further traffic jams," said Councillor Peter Box, chairman of its economy and transport board.
We further addressed the trafficking of the two mutant proteins by performing pulse chase experiments.
We further analyzed vesicular trafficking of APP in cultured hippocampal neurons, in which calsyntenin-1 was reduced by RNAi.
The Ser667Phe mutant will be a useful tool for further investigating the trafficking of band 3 and its interactions with GPA.
Further understanding of the intracellular trafficking of oligonucleotides may provide further enhancements in design and ultimate potency of antisense oligonucleotides in the future.
Previous studies showed that the size and surface properties (chemistry and charge) of NPs affected specific endocytosis pathways1,2, which further determined the intracellular trafficking of the NPs after their cellular entry3.
Following the confirmation of endosome transport, we further investigated the intracellular trafficking of BLPs using Lyso Tracter® Red, a tracing marker of acidic organelles.
