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It has been suggested that for cytostatic agents, assessing further time to progression after randomizing stable patients to continue vs stop a therapy could provide proof of benefit.
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A further analysis of time to progression to AIDS alone indicated that an estimated 4%, 13 % and 17 of infected children will have developed AIDS by 6, 12 and 18 months of age.
Further end points were time to progression, HRQOL, and treatment toxicity.
Further studies with a longer follow-up defining time to progression and survival should be planned.
The impact of intermittent chemotherapy on measures of cancer control, such as time to progression and survival require further study.
Surgical treatment suffices for the majority of NETs, but malignant, recurrent, and metastatic tumors need further treatment in order to gain a lengthening of time to progression [ 65].
(F ) A time to progression study for mice bearing subcutaneous LNCaP/AR-WT LNCaP/AR-WTsolid lines/AR-F876L (dashed lines) xenorrafts further highlights the genotype-dependent pharmacology of enzalutamidashed
Median time to progression is 12.4 months.
Time to progression (TTP) was defined as the time from the date of registration until the date of disease progression.
The median time to progression was 3.5 months.
Median time to progression was 5.1 months (95% CI: 3.3 6.7).
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