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The metastable state is important because it traps and holds the excitation energy, building up a population inversion that can be further stimulated to emit radiation, dropping the species back to the ground state.
Although fascinating in itself, this research has been further stimulated to an increasing degree by the appreciation of the critical importance of EGF signalling in cancer.
In the first place, these results suggest that cells having substantial heparanase activity cannot be further stimulated to produce exosomes by the addition of proheparanase, suggesting that saturation occurs at high levels of heparanase expression.
This phenomenon was first discovered when cells were passed in culture until, after approximately 50 cumulative population doublings (CPDs), they could not be further stimulated to proliferate and reached the so-called Hayflick limit (Hayflick, 1985).
With TGFbeta1 injection and treadmill running (TTR) the high level of Col1a1 expression at Day 5 (Acute group) was maintained, and Col3a1 and Col5a1 expression was further stimulated to 13.2-fold and 17.9-fold relative to naive levels.
Similar to our finding that neutrophils from SS patients showed no increase in effect upon barrier function following treatment with fMLP, Botha and colleagues have demonstrated that neutrophils from traumatically injured patients subjected to a second inflammatory stimulus (platelet-activating factor) could not be further stimulated to produce superoxide when treated with fMLP [ 37].
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Functional and pathological studies on this enzyme further stimulate to understand its structure and the structure function relationships.
To further stimulate individuals to work as fast as possible a 2,500-ms 2,500-ms window was used.
Krasnoyarsk's industrial growth was further stimulated by the evacuation to the town of many factories from the west in World War II.
Our research may further stimulate others to design novel biological materials at single chiral amino acid level, and may broaden the applications of designer D-form self-assembling peptides in clinical and medical nanobiotechnology.
This may further stimulate GPs to use the ICPC codes for work related problems.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com