To check the structural flexibility of the enzyme in both aqueous and nonaqueous environments, further simulation is needed to compare the structural basis of the enzyme.
Although, this procedure somewhat defines the folding pattern of NS4a in NS3 protease domain but further molecular dynamics simulations are needed which will provide some new insights about the folding of NS4a and its involvement in the stabilization of NS3 protease domain.
Further studies with longer simulations are needed to demonstrate larges implication of nitrification on seasonal-to-interannual and longer timescale variability of new production.
Further experiments and computer simulations are needed in order to validate these predictions.
Further experiments and molecular dynamics simulations are needed to validate these predictions.
Again, molecular dynamic simulations are needed to further investigate how the peptide influences the conformation of pazopanib.
Clearly, molecular dynamic simulations are needed to further investigate the preferred binding orientation of the hydroxyl group of abacavir.
More research studies, preferably qualitative studies that identify how students engage cognitively when they interact with visuohaptic simulations, are needed to further explain this result.
That is because when examining extreme events, many simulations are needed to generate a robust result.
Further investigation (e.g., by simulations) is needed to evaluate these possibilities.
