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For every population, six simulated haplotypes were used as a pool for further simulation.

Further simulation parameters are summarized in Table 1. Figure 5 Illustration of the simulated HetNet scenario.

Further simulation experiments were then carried out.

Through further simulation, p = 0.9 is suitable for most situations.

Further simulation parameters are depicted in Table 1.

Further simulation details are shown in Fig. S6.

A further simulation was run on Piz Daint using (2times10^{12}) (2 trillion) particles.

However, the further simulation does not result in the increase of this energy value.

They will not be extended to another stage without further simulation.

The optimum value selected for further simulation is 100,000 for α = 1.65.

Different split rates larger than 10% are necessary to be used for further simulation.

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