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In addition, analysis of MGMT promoter hypermethylation was also performed, and comparable promoter DNA hypermethylation was found in the anaplastic PXA samples as well as in the one grade II tumor further relapsing as an anaplastic PXA (Additional file 3: Figure S2).
Immune tolerance to inhibit further relapsing autoimmunity was induced by intraperitoneal injection of 250 μg YTS191, CD4 depleting monoclonal antibody followed one week later by the intravenous injection of 2 × 10 splenocytes chemically coupled to spinal cord homogenate (Ag-Splenocytes) as described previously [ 12, 17].
Similar(57)
CR or CRp was maintained for 7 to 10 months before death or further relapse.
The demonstration that neomycin resistance gene transfected genes in reinfused marrow may be detected in relapsed disease suggests that contaminated marrow may at least contribute to further relapse (Rill et al, 1994).
A further relapse into either could spell doom for Mr Saakashvili's already battered leadership.
This restores the balance of bacteria and prevents further relapses.
The one relapsing patient received additional immunosuppressive medication for 38 weeks which then could be stopped without further relapse.
Considering his poor response to medical therapy, a total colectomy had been performed 2 years before without further relapses of his condition.
Less than 1 mm of posterior relapse can occur after mandibular setback via IVRO, but the risk of further relapse is low and overcorrection is not commonly indicated [89].
We obtained an optimal response with definitive control of inflammation, without further relapses, since rituximab was administered with no more decrease of BCVA at 34 months follow-up (Fig. 3).
At first full recovery is the norm, later patients accumulate deficits and ultimately most convert to a secondary progressive phase (SPMS), characterised by deficits that increase in the absence of further relapses.
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