Reduced invasion of human intestinal epithelial cells, as compared to other serovars, further supports the reduced ability of this serovar to cause intestinal infection, however, further experiments are necessary to determine which genes are responsible for this phenotype.
However, the ADP/ATP ratio in the wild-type strain was three times lower than in the Δ pkaA strain, further highlighting the reduced ability of this strain to sense, internalize or metabolize glucose (Fig. 7g).
Introducing the R100 mutation further reduced the ability of hproNGF to induce pain.
Moreover, their immature shape and possibly other defects may have further reduced their ability to properly deliver oxygen to tissues.
However, 1 μM selenium supplementation further reduced the ability of HEK-TXNRD1_v1 cells to migrate.
In addition, the lower-than-anticipated event rates, possibly reflecting the comprehensive background management of cardiovascular risk in both arms (4, 8), and less-than-projected separation in A1C between the glucose treatment groups may have further reduced the ability to detect an effect reliably.
According to the EAM, NSSI is utilised to regulate negative emotion, whilst the after-effects of NSSI (e.g. shame, guilt) fuel further negative internal experience and reduced ability to cope over time, and NSSI re-occurs.
Further, the ACL group had a reduced ability to control head motion during gait, as indicated by reduced regularity in VT.
In addition, RAW 264.7 macrophages show reduced ability to migrate under hypoxic conditions, which further supports macrophage localization to the tumor edge and not the hypoxic tumor core.
We further show that mutant tau with N279D substitution has a reduced ability to bind to microtubules and to promote their assembly.
