On the basis of the evidences provided here (Additional file 2: Figure S1, Figures 1, 14, 15, 17, 18, 19 and 20), we further propose here that C. botulinum needs to be reclassified in to 4 different (sub -species, asub -speciesly believed by masy researchers [ 16].
To increase the applicability of genetic algorithms as the one proposed here, further research should study large population cohorts, and include different ethnic groups.
Some possible ways of further improving the methods are proposed here.
We further expect that the method proposed here will provide better results when a better signal-based speech quality model becomes available.
For the less robust two-step shapers, an effective 'online tuning' scheme is also proposed here to further improve its performance in a damped nonlinear system.
The adjustment method proposed here goes further than identifying differences in age and sex composition of those who agree to participate and those who refuse, looking within specific age- and sex- groups for evidence of systematic differences between the tested and those who refused.
More generally, we hope that the model proposed here will further stimulate experimental and therapeutic studies designed to test and modify the various interacting cognitive influences described here.
Confidence in our time estimates as proposed here gains further support by the dates we obtained for the inter-island splits of the three phasmid genera that have members on both Mauritius and Réunion.
The reported analyses further show that the separation strategy proposed here can allow the assay of charged species with a significantly greater resolving power than that possible using the capillary zone electrophoretic technique.
Short of fine mapping or, ultimately, deep sequencing of regions implicated by each method, further evidence for the architectural implications proposed here may be sought in the extant genetic literature.
