Sentence examples for further perturb from inspiring English sources

In this study, we demonstrate that low doses of arsenic exposure mitigate or mask p53 function and further perturb intracellular redox state, which triggers persistent endoplasmic reticulum (ER) stress and activates UPR (unfolded protein response), leading to transformation or tumorigenesis.

As the mtDNA haplogroups were characterized by distinct sets of variants, it is not surprising that certain mtDNA haplogroups could affect respiratory chain functions and may further perturb the crosstalk signaling.

The explanations, or lack thereof, seemed to further perturb the already irritated Senator who quickly cut to the chase: "You let the banks violate the law and you don't know what you'll be telling the homeowners?" It was a Capraesque, flash-bulb moment right out of Mr. Smith Goes to Washington, but alas, the turtles were back in their shell.

We evaluated embryonic development following heat shock at the 50% epiboly stage to determine whether increased EWS-FLI1 expression would further perturb embryonic development.

For example, given that genomic instability, defective DNA repair, and deregulated transcription are some of the hallmarks of cancer, drugs that further perturb these processes may be specifically toxic (i.e., synthetically lethal) in cancer cells.

Subsequently, this local aggregation of IL-4 secretors will further perturb the microenvironment, including a skewing of the differentiation of naïve CD4+ cells to the production of more B-cell helpers and an inhibition of the CD8+ cells.

Investors were further perturbed when Moody's cut its ratings for state-owned companies in Dubai, underlining the extent of the Gulf emirate's debt woes.

Measurements of these observables, or error syndromes, must also be performed in a quantum non-demolition way (projecting without further perturbing the state) and more quickly than errors occur.

The introduction of the test tube, as well as the air space in and around the tube, further perturbs the dose distribution.

It may therefore be possible that the collagen remains in a pre-gelatinised state that is difficult to distinguish from native collagen without further perturbing the system by attempting to extract the collagen and examine its physical properties or integrity.

It is possible that nicotine, through promoting cyclin D1/E2F signaling, prevents ATM/Chk2 signaling to be activated or interferes with Chk2 phosphorylation process in response to DNA double strand damage induced by either γ-irradiation or BP, and further perturbs the growth restriction.