The costing algorithm, in particular, requires further testing and refinement.
These individuals in particular require further investigation and specific treatment, with early antiretroviral therapy and cotrimoxazole prophylaxis.
As with any measures, the tools we used are subject to bias and the TFEQ in particular requires further validation in a mid-age population.
While our understanding of the pathophysiology of neuropathy and ischemia leading to DFUs has increased in recent years, insights into underlying alterations in fibroblasts in the chronic wound environment in general, and their participation in metabolic memory in particular, require further study.
Crime in particular requires immediate attention.
Further work in this area is clearly warranted, and in particular, further studies are required to determine whether the CoREST/REST repressor complex is recruited to the virus genome during neuronal latency.
In particular, further work is required to determine how the number and chromosomal distribution of divergently selected genes affects ecological speciation.
The evidence from epidemiological studies published to date have not been consistent and, in particular, further studies are required to identify whether longer term (well beyond 10 years) RF exposure might pose some health risk.
Further research is required, in particular, with respect to competitive strategies which incorporate the specific affordances of digital technology.
In particular, further research is required to determine the size of any Hawthorne effects.
Further studies are required, in particular, those examining the strength and duration of aspirin use that may be required to exert a protective effect.
