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Further pQCT data collection is indicated.
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Peripheral quantitative computed tomography (pQCT) data from the fifth lumbar vertebra show that mice lacking myostatin have approximately 50% greater trabecular bone mineral density (p=0.001) and significantly greater cortical bone mineral content than normal mice.
pQCT data are novel in this cohort.
Further pQCT research is necessary to identify regions of interest that are prone to fracture risk in people with chronic diseases.
Table 5 summarises the pQCT data from the tibia, and Fig. 1 compares each athlete group with the sedentary control people.
These authors have also discussed the fact that pQCT data compare well with other methods of assessing bone density such as histomorphometry and dual energy X-ray absorptiometry.
The International Society of Clinical Densitometry has highlighted the need for further pQCT research to determine other regions of interest (ROI) that are predictive of fracture risk in people with chronic diseases [ 12].
Theoretically, loss to follow up may also bias sample statistics, such as mean BMDc, for instance due to reducing the number of participants with low birth weight, but this is unlikely to have led to spurious associations being observed between birth weight and pQCT data [22].
Therefore, in this retrospective clinical study, HR-pQCT data obtained from patients with fragility fractures and T-scores ≥ −2.5 (n = 71) were compared to corresponding data from patients with fragility fractures and T-scores ≤ −3.5 (n = 56).
Women with bound feet had significantly lower QUS values than age-matched women with normal feet; this was supported by HR-pQCT data.
pQCT-data obtained for the female femurs indicate large differences in bone size between the RJ and WL populations, but also indicate that female biological replicates should be relatively homogenous with the exception of RJF19.
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CEO of Professional Science Editing for Scientists @ prosciediting.com