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To date, the combination of immunotherapy with targeted therapy has demonstrated potential as a cancer treatment strategy, but further optimizations are required and caution must be taken to avoid toxicity.
For preparation of NLC/SI and NLC/GM, further optimizations are required to achieve desired PS and PDI.
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Further optimization is required.
The post-process surface treatments restored corrosion performance to pre-processed capabilities; however, further optimization is required to achieve maximum corrosion resistance.
These results demonstrate that, although chimeraplasts are fairly effective at targeting episomal DNA in primary cells, further optimization is required to increase the efficiency for targeting integrated genes.
The obtained adsorption isotherms show that adsorption can be a promising technology for the separation of long-chain n-aldehydes having a very similar boiling point; however, further optimization is required.
This result suggests that further optimization is required in controlling the biomechanical and/or the biochemical environment if such stimuli are to have beneficial effects in generating functional cartilaginous tissue.
Although further optimization is required, preliminary results indicate that the I2S-LWR can achieve a core damage frequency (CDF) from internal events less than 1.01 × 10−8/ry, including reactor vessel ruptures.
This suggests that further optimization is required to improve transformation efficiencies and for more rapid identification and separation of mutants before they are visible in cultures.
Further optimization is required to develop the most effective probe to fulfill this urgent clinical need for noninvasive imaging of hormone-dependent diseases.
However, further optimization is required, testing its reliability and validity in several different patient groups, leading to an international multidisciplinary protocol with the active involvement of health care providers.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com