Further modeling needs involve an understanding of the chemistry of these materials and reflect the more modern approach to the physico-chemical structure of petroleum in order to more correctly predict the onset of precipitation as well as the location and amount of the sediment deposition in the producing wells and in oil-transport pipelines.
Further, these models need many assumptions for the underlying model.
We find, for example, that the spatial heterogeneity of key molecular actors can explain the difference in filament lengths in cells on different micro-geometries partly, but to explain the full extent, further model assumptions need to be added and experimentally validated.
In my upcoming memoir, Washed Away: From Darkness to Light, I detail my experiences in the dark side of the industry, although my mission is not to vilify the business, but to educate the public and to further support why models need workplace protections and health standards.
Mechanisms of action are broadly understood but they need to be further defined and models need to be developed to better evaluate modes of action.
It is reasonable to believe that model misspecifications will lead to imprecision in the statistical power and in the case in which the model is so uncertain that further model building needs to be done, the analysis will suffer from uncontrolled type I error rate.
Both models need further benchmarking and development to reproduce all switching transient behaviors properly.
The candidate models need further development and implementation, which address issues such as hierarchical inputs, calibration/validation, and implementation.
For the use of single-frequency altimeters (e.g., GFO) for sea level studies during high solar activity period, ionosphere models need further improvement.
Whether mutations of TIN2 would affect the pluripotency of PSCs and the efficiency of iPSCs reprogramming in Tin2-related dyskeratosis congenital (DC) disease models need further investigation.
