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The risk of type 2 diabetes increases among adolescent and young adult women with PCOS (41), with obesity further increasing risks of diabetes and of hypertriglyceridemia (42).
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Correspondingly, dialysis duration beyond 5 years shows further increasing risk, as patients continue to accumulate comorbidity.
Among late-onset cardiomyopathy cases, the development of diabetes and ischemic heart disease further increased risk.
This lowered capacity of hepatic xenobiotic clearance is often associated with abnormal drug reactions and further increased risk of liver disease and cancer in the elderly [31].
Individuals with shorter cilia would potentially also be at further increased risk of poor mucociliary clearance due to the mechanical disadvantage conferred by both defects.
In addition, men reporting a longer duration of prostatitis symptoms had a further increased risk of prostate cancer (P trend = 0.003).
Women who are obese are at a further increased risk of developing breast cancer [ 60, 61].
A post hoc analysis suggests further increased risk with even longer exposure periods.
The further increased risk of OAMZL detected when only Cp-associated cases were analysed is consistent with this hypothesis.
In postmenopausal but not premenopausal women, obesity is linked with a further increased risk of developing breast cancer.
Furthermore, the combination of both predictors was associated with further increased risk for developing an infusion reaction.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com