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Further, increased expression of neuron-specific enolase, S100B and decreased expression of (post-synaptic density-95, synaptosome-associated protein-97) synaptic protein indicated neurodegeneration.
The combined treatment of GCTSCs with Aza and PBA further increased expression of all analyzed genes.
Further, increased expression of Sema4A is required to promote inflammation of RA.
Further, increased expression of heparanase is correlated with the high metastatic capacity of tumor cells [ 77].
Further, increased expression of miR-335 is associated with elevated lipid metabolism in obese mice [ 31].
Cordyceps sinensis treatment and hypoxia exposure further increased expression of Nrf2, HO1, and MT levels compared to normoxic cells.
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Consistent with this idea, further increasing expression of Dfmrp using two copies of UAS- dfmr1 does not cause nuclear localization nor axonal looping or bifurcation (Supplementary Fig S5).
First, the presence of an endogenous ligand in relatively high concentration (or at sufficient concentration to saturate the receptor) that also exhibits higher affinity for PPARβ/δ as compared to GW0742 could explain why an exogenous ligand does not further increase expression of a type II response gene.
Further, increased expression level of spermine oxidase was observed in WT OIR retina, suggesting increased oxidation of polyamines in OIR retina.
Further, WFA increased expression of osteogenic genes with increased expression of transcription factor associated with osteoblast differentiation.
WDR5 F266A +dox further demonstrates increased expression of ectodermal and mesodermal markers.
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