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However, the presence of non-replicating pathogens has a further increased effect on virulence as the optimal replication fraction increases (Figure 2).
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The HPC is much better retained in the silica-titania xerogels than in silica xerogel, but the increase of titanium content shows no further increasing effect.
Interestingly, a NPM/B23 T199A/S4A double mutant further increased the effect suggesting that both phosphorylations need to occur to obtain a pronounced effect on centrosome duplication.
Overnight pre-incubation with Sb further increased the effect as the number of bacteria dropped to 0.016±0.007×106 CFU well−1, corresponding to 0.37% of total bacteria.
Addition of plasma further increased the effect of exogenous TNF-α.
In addition, PMA further increased the effect of apicularen A on the microtubule networks and on α-tubulin levels.
Consequently, exposure to DE, which has been shown to increase vasoconstriction (Peretz et al. 2008), might have further increased the effect in both strains in these experiments.
The inhibition of HSP70 has further increased the effect of growth arrest and apoptosis activation triggered by H. pylori in gastric epithelial cells.
Reverse Transcription-PCR (RT-PCR) showed a significant increase in the expression of the spliced isoform of XBP1 (XBP1S) after treatment with 100 μM ceramide for 6 h, and prolonged incubation with ceramide for 12 h further increased this effect.
To investigate if the soluble scTCR yield in the periplasmic fraction could be further increased, the effect of sucrose addition was assessed both in uninduced and IPTG induced cultures.
The selective AEBS ligand PBPE (10 μM), however, was able to regulate HDJ2 farnesylation itself in the absence of R115,777 (lane 7) and further increased the effect of R115,777 (lane 8).
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