Sentence examples for further increase complexity from inspiring English sources
Under proposed value based pricing, this will create severe implications since potentially sorafenib will carry 2 prices, which will further increase complexity factor of reimbursement process.
To further increase complexity of the cellular microenvironment, microstructures composed of bioactive heparin gels were fabricated across the surface of 400 nm pitch patterned substrates.
Imposing differing behavioral experience following developmental Pb ± PS results in additional divergence of PTHM profiles, again in a sex, brain region and time-dependent manner, further increasing complexity.
The behaviour of such model systems, not only as isolated spin systems and in dependence of their coupling to the substrate/environment but also as elements of quantum-coupled systems, may provide a new basis for experimental insight into quantum behaviour at further increased complexity.
Unfortunately, irradiation further increases complexity of management, due to a combination of three factors: a) low likelihood of spontaneous closure; b) poor healing and high risk of dehiscence following surgery on irradiated bowel; c) delayed or impossible adjuvant or palliative therapies in presence of an ECF [4].
The increasing recognition of within-tumor cellular and genomic heterogeneity further increases complexity.
More complex quaternary structures such as obligate hetero-trimers further increase the complexity of the docking steps, requiring more computational effort and more models.
(c) the long noncoding transcript may bind proteins to further increase the complexity of regulation of the adjacent protein-coding gene (cis function).
To further increase the complexity of the logic system, another enzyme glucose oxidase (GOD) was added into the films, designated as P(NiPAAm-co-DMEM -HRP-GOD. INiPAAm-co-DMEM -HRP-GODNiPAAm-co-DMEM -HRP-GODcose iNiPAAm-co-DMEM -HRP-GODlyzed by GOD iNiPAAm-co-DMEM -HRP-GODoduced H2O2 in situ was recognized and electrocatalytically reduced by HRP and mediated by Fe(CN)63−.
Moreover, to enhance the combination of the deposited material, the choice of suitable deposition medium (gas or liquid phase) and the addition of surfactant were also carefully considered, though they would further increase the complexity of the fabrication [42].
A further increase in complexity during evolution could have been to replace a simple type of cooperativity (pure successive paring) by an elaborated FP interplay based on already pre-formed aggregates of fusion proteins.
