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On-chip integration of low-noise preamplifiers may further improve sensitivity performance.
Higher WGS coverage would further improve sensitivity for detection of subclonal structural variations, which is important for samples with low tumor purity or high intra-tumor heterogeneity.
This follow-up work provides an optimized structure design based on the integration of double 60° bend waveguides and modified center-defect photonic crystal microcavity to further improve sensitivity.
Imaging these new probes with our technique will further improve sensitivity of calcium signal measurements.
Since the key width of an index (w) here is less than the read length, we are able to apply the mask at all possible starting positions offset from the beginning of the read to increase the number of lookups performed per read and thus further improve sensitivity.
It is possible that extending the CILIOGENESIS data set to include factors regulating the ciliary responsiveness to Hedgehog or Wnt activators or suppressors could further improve sensitivity.
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For better detection, the affinity maturation can be used to further improve sensitivities of the Fab fragments if needed [ 44].
However, further improved sensitivity and accuracy of the devices are required, so that the development of a novel nanostructure design with special optical properties for high sensitivity and selectivity has become a priotiry.
This stage adds extra cluster pairs to the output, further improving sensitivity.
The inclusion of the IgG test result modestly further improved sensitivity.
Combining biomarker miRNA pairs within the same set further improves sensitivity and specificity (Fig. 3 and Table 2).
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