Sentence examples for further important limitations from inspiring English sources

Further important limitations of the present research deserve to be highlighted.

These data have two further important limitations.

The further important limitations of our study are: (a) due to the nature of the pre-2012 contracts with home oxygen providers in England, we do not have concordance data on actual oxygen use therefore the hospital admission rates amongst COPD patients prescribed LTOT could not be corrected to actual oxygen use; (b) No data was available for current smoking habits of LTOT users; (c).

A further important limitation of the study is that the data are cross-sectional.

A further important limitation of the study is the use of consultation vignettes to seek GP's reported behaviour.

A further important limitation was that not all patients had a blood culture taken and that those cultured were sicker than those who were not.

A further important limitation is that the use of phenobarbitone and morphine may have resulted in overdiagnosis of moderate-severe encephalopathy in the infants who were cooled.

A further important limitation is that in the significant proportion of patients (~40%) with both S. aureus and CNS, this assay alone cannot distinguish for the presence of MRSA or other resistance determinants being carried by S. aureus.

A further important limitation of this study is that diagnoses were clinical, without neuropathological correlation: this leaves open the possibility that at least a proportion of participants in this series had a histopathological substrate outside the FTLD spectrum.

If confirmed by further studies, and despite important limitations related to sonography, this technique could serve as a screening test in patients at risk for raised ICP, when invasive monitoring is not possible or is not clearly recommended.

However, the development of cellular and humoral responses specific for vector components [ 110] and/or for the transgene [ 111] posed important limitations and triggered further research to solve this issue and develop new gene therapy vectors [ 2].