They further identify a specific RB1N region, predicted to confer protein binding (Hassler et al., 2007), as responsible for mediating the interaction with XRCC5 and XRCC6.
Further, we identified a specific plasma miRNA signature (miR-23 and miR-223) that may serve both as predictor and biomarker of response to anti-TNFα/DMARDs combination therapy.
We further identify an opossum specific gene that appears to serve as an outgroup to all TAARs, tentatively called TAARL (trace amine associated receptor-like).
Direct NF90 depletion is likely not a viable therapeutic approach because of its multifunctional properties; however, further analysis may identify a specific site(s) in NF90-mediated regulatory pathways that show greater specificity for interrupting the dengue virus life cycle.
We further identified IP3R1 as a specific regulator of their speed fluctuations and migration persistence.
We further identified NP-specific γδ TCRs on a single cell level.
We further identified specific residues within the pore module that determine unitary conductance, pore blockage and ion selectivity for divalent and monovalent cations and anions.
Within each category, we further identified specific domains to capture common response themes.
Our Targetscan analysis further identified the luminal-specific genes RANK, NOTCH3, ELF5, ESR1, HEY2 and KIT as potential targets of these primate-specific miRNAs (Fig. 3c).
A smaller number of lineage-specific genes with an incomplete open reading frame across different Arabidopsis thaliana accessions are further identified as accession-specific genes, most likely of recent origin in Arabidopsis thaliana.
Further, we identified a neuronal-specific protective mechanism, that is, 14-3-3 γ/p- β-catenin Ser37/Bax axis in ischemic neurons, dependent on 14-3-3 14-3-3 14-3-3n Ser37 interactions in the nucleus.
