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Further, highly expressed and fast evolving functional miRNA that are lacking sequence conservation might still be missed.
Further highly expressed genes (all named by the gene name) were grouped together according to their known biological function and pathway.
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We further divided highly expressed genes into stably expressed (108 genes) and variably expressed (168 genes), based on the 10 pg dataset (Methods).
Further, although highly expressed in the tumour tissues, ITGA6 seems not to be involved in HPV infection due to the low HPV infection rate.
The score can be further adjusted for highly expressed genes which takes into account the level of variance in expression across all tissues in order to reduce the contention of highly ubiquitously expressed housekeeping genes.
115 Further, EpCAM is highly expressed on the surface of chemotherapy-resistant ovarian cancer cell lines.
Further investigation of highly expressed genes may be warranted to determine what functional roles the highly expressed sequences may play in soybean seeds.
Using stromules as an indicator, the viability of this strategy could be further tested for highly expressed and stable transgene products.
Tumor samples with more than 60% of stained cells (the median percentage of stained cells in only positive cases) were further categorized as highly expressed for the association with Amp13q34.
Further examination under highly expressed (>75% quantile) and lowly expressed genes (<25% quantile,) condition revealed that among highly expressed genes XBSeq performs only slightly better than DESeq, while XBSeq has much better AUC than DESeq among lowly expressed genes (Supplementary table S3), indicating the importance of background estimation for true signal estimation.
Our data add IL-1β and Nlrp3 as further cytokine network factors, highly expressed in the skeletal muscle during systemic inflammation.
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