Employing NAC fatty acid mimics to develop further high-throughput assays for individual enzymes in the FASII pathway should aid in the discovery of new antimicrobials.
This indicates that the cancer-associated signal transduction pathways in mammary tumourigenesis and lymphomagenesis are at least partly different and warrants further high-throughput IM studies.
The identification of germ line variants that affect the expression of longevity-associated genes will facilitate further high-throughput genetic epidemiologic studies of human aging.
Further, high-throughput sequencing of RNA (RNA-Seq) generally requires its reverse transcription, with the processivity of available reverse transcriptases (RTs) limiting even single molecule cDNA sequencing (e.g., Pacific Biosciences) to <2500 nt (Sharon et al., 2013).
This work has also paved the way for further high-throughput SNP typing that may reveal additional factors, including regulatory (non-coding) sequence variations commonly found in immune response genes beyond the HLA region, as well as coding sequence variations that are also common in genes encoding killer immunoglobulin receptors (Bashirova et al. 2006; Parham 2005).
Further, high throughput methods of single cell sorting (such as fluorescent activated cell sorting or FACS) are now routines and can be used upstream of the MDA reaction [24].
This amplified product, representing the composition of the initial DNA mixture, is suitable for further high throughput genomic analysis.
Further, it achieves higher throughput with fewer computations at the receivers.
However, once a multivariate model has been built and the most important spectral features identified, experimental time could be easily reduced to around 10 mins per sample further increasing high throughput possibilities.
Moreover, analysis of sample mixtures combined with MS detection further enables high throughput and sensitivity of detection.
