Sentence examples for further higher affinity from inspiring English sources

Further, higher affinity of IL13 to IL13R α2 allows for sequestration of the ligand away from IL13R α1.

Additionally, for cases in which we found distinct affinity-conferring mutations scattered across different clones, we combined mutations together to investigate the possibility of even further promiscuity and higher affinity.

This suggests that dithio-substitution can lead to further development of higher affinity of ligands against E-selectin.

In this work we have created the Mycobacterium tuberculosis PknB pharmacophore model which is can be used for further development high affinity compounds.

Also, C4BP and factor H bound specifically to CS-A on the sensor chip but at a lower response/molecular weight ratio than that of C1q, further supporting C1q's higher affinity for CS-A than that of C4BP or factor H. In contrast to C1q and factor H, C4BP demonstrated a slow dissociation from CS-A, revealing a rather high stability of the complexes once they had formed.

We hypothesized that further optimization of ligand with higher affinity would be able to improve in vivo tumor-targeting capacity.

Quantification of the interactions between GDI-1 or GDI-2 and Rab10 using in vivo FRET further confirms that GDI-1 does possess higher affinity towards Rab10.

Further, it binds specifically and with a higher affinity to the general anesthetic binding site on apoferritin (16) as shown by isothermal titration calorimetry (ITC).

It is possible that further mutagenesis and screening may select for scFvs with higher affinity for the cell surface target [ 37, 40].

The MHC-1 alleles for which the epitopes showed higher affinity (IC50 < 200) were selected for further analysis (Table 2).

This further confirms that Arb interacts with indole rings, but with a higher affinity when indole is incorporated into lipid membranes.