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The mechanistic disease computer-based model can further function as a useful biological knowledge repository with a common universal language (mathematics).
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The application of this design is realized in a diffuser micropump that further functions as a microdroplet ejector with the introduction of a nozzle plate.
Initially identified in DNA damage repair, ATM-interactor (ATMIN) further functions as a transcriptional regulator of lung morphogenesis.
Participant observation further functioned as a source of insight into pain experiences, coping strategies and encounters between patients and healthcare professionals.
In this assay, the presence of target mir-196a2T circularizes the padlock probe and the mir-196a2T functionednctioned as a primer to initiate the next round of RCA reaction in the presence of Vent (exo-) polymerase.
The fact that the terminal hydroxyl groups of PEG can be readily activated by Fe acac 3 to further function as coinitiator for the ring opening polymerization of CL towards forming triblock macrodiols (PCL-PEG-PCL, PCEG).
(II) HDAC6 deacetylates Hsc70 and DNAJA1 and enhances their interaction, which might further modulate their function as a chaperone pair.
The COM1 contains a putative ELL domain, which further corroborates its function as a transcription regulator.
Thus modifications or interactions with further partners could function as a dynamic relay, which affects conformation or flexibility of the binding interface.
To further elucidate brain function as an endophenotype, we used functional high-field magnetic resonance imaging at 9.4 T as a translational tool to look for disease specific alterations, which again led to the observation of functional alterations of the LHb.
The interaction of the protein with ribosomal A-site of bacteria further proposed its function as an aminoglycoside antibiotic resistance conferring protein.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com