Suggestions(2)
Exact(2)
It received written evidence from a further four individuals.
A further four individuals were classified as obligate mutation carriers on the basis of reconstructed haplotypes and/or their position in the pedigree.
Similar(58)
Secondly, to test the generality of the results, a further four individual plants were selected to represent a range of leaf morphologies (glabrous, intermediate, pubescent) and gall types (flat leaf and cone leaf galls) (Table 1).
A further five individuals were kept as standard controls (wild-type), developing in the Georgia Institute of Technology aquarium.
Lewy bodies in the SN were found in only seven individuals, with a further two individuals having Lewy bodies in the other areas examined.
Screening of TUBA3 in a second cohort of patients with cortical anomalies identified a further six individuals with de novo mutations in TUBA3.
Since the completion of this study, we have begun prospectively screening patients with PDAC for HER2 amplification using this diagnostic approach, and identified a further two individuals (of eleven) with HER2 amplification.
Although animals from the Hesse region belong to a distinct cluster, introgression is also widespread with 43.8% of animals showing ≥5% introgression from other populations and a further two individuals (12.5%) clustering entirely with other populations (France, Eastern Europe and Norwegian clusters).
Given our initial findings, we reviewed the exome data at the other PP2A-B56 subunit genes, which revealed de novo mutations in PPP2R5B (c.482C>T [p.SeRefSequ]; RefSeq accession number NM_006244) and PPP2R5C (c.468_470delAAC [p.ThRefSeql]; RefSeq accession number NM_001161725) in a further two individuals.
A further seven individual key informant interviews were undertaken.
Further, two individual studies with multifaceted interventions including a didactic component, provision of online resources, and small group work showed improvement among medical students in EBP self-efficacy [ 20] and strength and quality of evidence used in clinical practice [ 27].
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