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As all changes are logged (critical and otherwise) and there is no further filtering of this information, the role of CHEX is to aid information acquisition rather than to provide any deeper analysis of the change.
Further filtering of data, based on expected retention time ranges, was performed.
However, further filtering of the SNPs for individual genotyping (see Methods) reduced dramatically the available SNPs.
New text boxes at the top of each column allow the further filtering of data according to these criteria.
Gene Spring Software 11.5.1 was adopted for further filtering of DEGs from normalized data through a series of quality control steps.
As with Phenol-Explorer composition and metabolism data, text boxes at the top of each column allow for further filtering of data.
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After further filtering out of probesets that may cross-hybridize with other genes based on the Affymetrix probe nomenclature, 52% (= 31,768) of the probesets were used for detailed analysis.
Probe sets were further filtered on the basis of a fold-change cut off of 2.0.
SNP call statistics subsequently determined by VCFtools and the raw SNPs were further filtered on the basis of quality (Q=100), thereby, additionally increasing the stringency of called SNPs.
After further filtering for multiple occurrences of a gene ID, 619 unique genes remained, of which 381 were downregulated and 238 were upregulated.
They were further filtered for absence of potential off-targets within the murine genome and transcriptome, by Blat (UCSC) and Blastn (NCBI) softwares, respectively.
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CEO of Professional Science Editing for Scientists @ prosciediting.com