Anyway, the process is a complex one and other important factors are also involved, further exacerbating the clinical setting.
She was pregnant by the age of 16 – further exacerbating the family's financial situation.
Further exacerbating the problem is how loosely journalists will throw these terms around.
Moreover, the regenerative capacity of skeletal muscle declines with aging, further exacerbating the problem.
Additionally, the demand for lower skilled jobs pushes wages down, further exacerbating the situation.
To further exacerbate the injury process, acidosis and the lack of ATP inhibit cellular mechanisms normally responsible for controlling excessive intracellular Ca2+, such as ATP-dependent Na+/K+ pumps and Na+, K+, and Ca+ channels [28].
Combined these findings seem to ascribe an important role for Sap9 in oral candidiasis, as the increased expression of a proteolytic enzyme capable of efficiently degrading Hst-5 may be a key event in the transition from commensal to pathogenic growth or may further exacerbate the infectious process.
In addition, ApoE4 has poor antioxidant properties, compared with ApoE2, and combined with its proinflammatory functions may further exacerbate the tumourigenic process (Miyata and Smith, 1996; Jofre-Monseny et al, 2007).
However, also other glomerular cell types, like endothelial cells, and podocytes have been implicated in the genesis of diabetic nephropathy, while inflammatory cells such as macrophages can further exacerbate the oxidative stress and inflammatory processes leading to apoptosis.
The fact that many key positions in the U.S. Treasury Department lack nominees or have proposed occupants awaiting Senate confirmation has further exacerbated the situation, with a demanding vetting process causing several potential nominees withdrawing from consideration.
