Large tidal volumes or pressure changes may further exacerbate damage to the pulmonary microvasculature, and it would therefore seem prudent to adopt a protective ventilation strategy.
The massive success of the film -- it is the highest-grossing musical biopic ever -- further exacerbates the damage the film has done, according to the lawsuit.
This probably further exacerbates oxidative damage by adversely affecting critical GSH related processes such as free radical scavenging, detoxification of electrophilic compounds, modulation of cellular redox status and thiol-disulphide status of proteins, and regulation of cell signalling and repair pathways [ 44].
2. Diabetes further exacerbates the cardiovascular damage, reducing vascular endothelial cell reactivity.
Conditions were further exacerbated by damage to crops and settlements by tropical weather events, notably Superstorm Sandy in October 2012.
Loss of physiologic function of normal α-syn and oxidative insults from microglia-derived free radicals further exacerbate neuronal damage, eventually causing neuronal death.
Liver injury and cirrhosis reduce the ability of the liver to metabolize and excrete drugs, which may further exacerbate liver damage.
The acutely injured brain is vulnerable to systemic derangements, such as hypotension, hypoxemia, or fever, which may further exacerbate neuronal damage [ 4- 7].
In the context of Cr VI) exposure, these reactive species may further exacerbate DNA damage in surviving and/or proliferating epithelial cells and thus promote initiating events in Cr VI) carcinogenesis (O'Brien et al. 2003).
Because inflammation further exacerbates radiation-induced tissue damage (Sonis, 2004b), reducing inflammation in pre-exisiting lesions provides a beneficial microenvironment for oral mucositis healing.
13, 15, 16 Chronic exposure to CS can lead to increased airway cell damage/death, which further exacerbates pulmonary inflammation through the release of damage-associated molecular pattern molecules (DAMPs).
