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Information on the conserved core genes, as well as those that may be involved in specific functions that define monophyletic groups, host associations, and plasmid-related behavior, will be valuable resources for future laboratory work (e.g., development of vaccines, diagnostics and therapeutics) as well as further evolutionary studies of this intriguing obligate intracellular bacterial group.
Further evolutionary studies will help to relate individual CNC to specific developmental processes.
These observations, derived from a single but highly informative gene, should stimulate further evolutionary studies of the Ciona genus.
Within the Coronator Group, the topology yielded was the same of that performed with all genes, demonstrating the potential of those genes for further evolutionary studies with this group.
However, a good understanding of phylogenetic relationships within radiating groups is key for further evolutionary studies into mechanisms and whether change is adaptive, due to drift in small populations or other phenomena [ 29].
The identification of the degenerate zinc finger motif (mainly based on the absence of one or several of the two cysteine and histidine residues) is however valuable information that could be compiled in further evolutionary studies.
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Thus, further evolutionary genomics studies of sperm-specific channels and transporters will no doubt shed novel insights into physiological roles of ion transport in sperm biology.
Further detailed evolutionary studies will be required to elucidate the evolutionary forces that may account for the patterns observed, and to determine which of these genes have contributed significantly to the evolution of M. tuberculosis.
Thus these results highlight genomic regions that are of particular interest for further functional and evolutionary studies.
This gene set will be of use to the vector biology community for further biological and evolutionary studies.
Here we describe a collection of 29,428 ESTs, which represent a valuable resource for further ecological and evolutionary studies in Bombus spp. and for comparative studies with other Hymenoptera and insects.
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