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Resection of the endolymphatic sacs at E14.5 led to an enlarged cochlear lumen in Slc26a4+/− mice but caused no further enlargement of the already enlarged cochlear lumen in Slc26a4−/− mice.
Further enlargement will also have a budgetary impact.
The instinct of NATO insiders has been to push further enlargement.
Apart from their qualms over further enlargement, they fear that it could upset Russia, with unpredictable implications.
Then further enlargement could become so difficult that NATO's first three new members may prove to be its last.
There are big divisions, too, over further enlargement, which is inextricably tied to NATO's relationship with Russia.
It has kept the door open to further enlargement of the EU in the Balkans.
Many EU members have cold feet about further enlargement of their club.
Opponents of further enlargement of the EU may be wrong, but they are not obviously crazy.
Would they be willing to ask E.U. citizens their opinion about further enlargement?
In many of them, voters seem strongly opposed to further enlargement.
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