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HI group had further elevated levels of pulmonary TNF-α compared to the OES group without hyperinflation.
Further, elevated levels of TNF-α along with activated expression of NF-κB, PCNA and CYP1A1, and downregulation of Nrf2 was observed in B[a]P intoxicated animals.
Further, elevated levels of HSPs have been observed in activated astrocytes to target those proteins for degradation [ 8].
Further elevated levels of nucleotide excision repair (NER) genes show a novel mechanism by which drinking GTPs prevents UV-induced immunosuppression [ 81].
Further, elevated levels of circulating insulin and C-peptide have been associated with an increased risk of colorectal and pancreatic cancers (11).
Further, elevated levels of DKK1 may negatively influence several important steps of bone metastasis, such as mobilisation, engraftment, and proliferation of prostate cancer stem cells to and within the bone marrow (Tian et al, 2003; Adams and Scadden, 2006; Lee et al, 2011).
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We further determined elevated levels of MMP activity as well as gene expression of MMP-1, TIMP, and RECK in stimulated immune-competent hemocytes.
Our proteomic analysis of ccRCC further suggests elevated levels of ribosomal and proteasomal proteins, putatively indicating a generally increased protein turnover in ccRCC as compared to non-malignant kidney tissue.
On further analysis, elevated levels of pretreatment serum folate were associated with a higher incidence of grade 2/3 diarrhoea (P=0.001) and grade 2/3 nausea and vomiting (P=0.032) compared to grade 0/1 toxicity.
Increased oxidative stress in OVX rat aortae is further supported by elevated levels of nitrotyrosine, an oxidative stress biomarker.
Immuno-labeling further demonstrated 152% elevated levels of the N-terminus characteristic of N-AChE-S in AD compared to NDC cortices (Median Test p = 0.03) (Fig 6D), together suggesting AD-associated overexpression of N-AChE-S in cortical neurons.
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