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With all products indicated for the treatment of acute attacks, a further dose should be given whenever the patient fails to noticeably respond to the treatment within 2 to 3 h (i.e., if the swelling continues to get worse).
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A first dose should be given to every accident victim, followed by two more doses several months later.
An equal daily antibiotic dose should be given to continuous and bolus administration group c.
The entire dose should be given 1 h before bedtime to improve sleep and minimise tiredness the following day.
A loading dose should be given to continuous infusion group to ensure rapid attainment of target antibiotic concentration b.
Consequently a high and safe dose should be given.
Therefore, a supplemental dose should be given immediately following every 4-hour hemodialysis treatment (Table 1).
This starting dose should be given for a maximum of 4 weeks.
Each SP dose should be given at least 1 month apart.
In any case, the last dose should be given beyond 12 weeks of age.
After the first does at birth the second dose should be given at six weeks, third dose at 10 weeks, and fourth dose at 14 weeks.
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