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A further disadvantage of using inter-species crosses to map A. majus mutations is that A. majus and A. molle differ in many morphological characters, including plant and organ size.
A further disadvantage of using CTVBs is the differences in the systems between England, Wales and Scotland, including different time intervals between revaluations, and the changes that might result from the recent political debate on the funding and functions of local government.
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One further disadvantage of pair-HMMs is that the algorithms that are used with the model cannot be easily parallelized.
A further disadvantage of this study is that data concerning antihypertensive use was only available after 1995, and only as DDDs, rather than number of patients being treated.
Where new work is implemented, it requires a leap of faith to use relatively untried materials that have the further disadvantage of apparent higher cost rather than follow the traditional route that will last for the period of civic memory.
A further disadvantage of heparins is their animal origin for several reasons.
A disadvantage of using too precise criteria is decreased flexibility.
One major disadvantage of using standardised patients is their expense.
Further disadvantages in using information from the Scottish dataset include potential inaccuracies in estimation of times between pregnancies due to misclassification of hospital admissions that could have been the result of the same event.
Further work will address the advantages and disadvantages of using the same versus different systems for grading evidence, further clarification of the included criteria, the need for additional criteria, and the perceptions of policymakers and stakeholders who do not have a research or health professional background.
Further work is needed to clarify advantages and disadvantages of using specific PRO instruments to measure relevant constructs and to identify the most useful batteries of instruments for NNRTI trials.
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