The clinical translation of stem cell-based Regenerative Endodontics demands further development of suitable injectable scaffolds.
Further development of efficient gene transfer techniques and keeping transplanted stem cells healthy have the potential to make biologic therapies more robust in promoting angiogenesis, tissue regeneration, and resolution of CLI symptoms.
Therefore, with further development of expansion and differentiation protocols, the use of cord blood stem cells can be extended to routine laboratory disease modelling and testing of therapeutic agents above and beyond the curative transplantation value of this biological material.
We believe that determining optimal conditions for GFP-based in vivo stem cells tracking may potentially contribute to further development of effective cell-based therapies in human subjects.
We report the further development of this slice model of CNS remyelination in the mouse cerebellum, brain stem and spinal cord.
More precise characterization of stem cells with identification of new, unique markers; improvement in isolation and transplant techniques; and further development of functional assays will ultimately lead to new therapies for a host of human lung diseases.
Despite these differences, immortalized cells as well as other emerging in vitro systems (e.g., primary cells, stem cells and 3-D culture systems) provide valuable mechanistic information that supports the further development of high-throughput toxicity screening assays.
Further development of the RSA technique enabled measurement of stem/cement interface motion, which was necessary to understand the behavior of polished stems and the failure patterns of stems with a rough surface.
(J) Further development of LRP.
