Existing statistical models employed to assess how changes in biomarkers impact on cognitive function are limited and need further development and the historic lack of standardisation in both sampling and analysis makes attempts at post hoc data harmonisation challenging.
Investment in novel technologies, research, standardisation and training is paramount for further development and implementation of SUTs across all sectors of the biopharmaceutical industry.
It is hoped that this review will assist in development and standardisation of methods in future and we discuss the areas of priority for further research to facilitate the development of guidelines to support meta-analysis of adverse and unintended outcomes data.
The development and standardisation of sensitive, valid behavioural tests which are suited to phenotype mouse mutants is both a responsibility and a challenge to investigators of mouse behaviour.
We have presented the development and standardisation of the MARISTAN Stigma Scale.
The development and standardisation of the intervention has been previously described [ 16].
Further simplification and standardisation of regimens would make scaling up treatment more practicable, but potentially increases the risk of XDR-TB development.
The feasibility and integration into daily clinical practice of these low-dose techniques require further investigation and standardisation.
Further streamlining and standardisation of these processes in needed to ensure that high-quality research can continue in the UK.
We conclude that the optimum use of microarrays in clinical studies requires further optimisation and standardisation of methodology and reporting, together with improvements in clinical study design.
