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Synthesis and evaluation of further derivatives as well as in vivo click experiments are currently under investigation.
Ten-eleven TETnslocation (TET) proteins are recently characterized dioxygenases that regulate demethylation by oxidizing 5-methylcytosine to 5-hydroxymethylcytosine and further derivatives.
As starting material for Suzuki-Miyaura cross coupling reaction, it was selected for the design and the synthesis of six further derivatives, with the aim to better define structure-activity relationships.
The keto-deoxy sugars have been found to be useful precursors for producing further derivatives.
Consequently, we have identified evocarpine as a hit compound for the development of further derivatives with improved antimycobacterial activity.
The metabolities found in vivo are identical with, or further derivatives of these rearrangment products, with one important exception: trichloroethylene.
Similar(51)
Generalizing this, one could consider the generation of character data from a sample as a derivation event, and the obtained character dataset as a further derivative instead of a sample-based characterization item.
Software covered by copyleft agreements can be modified in any way so long as the finished work and any further derivative works retain the same restrictions imposed on the original software by its author.
As in Cochrane and Saá-Requejo (2000); Björk and Slinko (2006), we consider good-deal constraints imposed as bounds on the Sharpe ratios (equivalently bounds on the optimal growth rates as in (Becherer 2009),) in the financial market extended by further (derivative) asset price processes.
Additionally, it allows further derivative data to be produced for tasks not easily expressible in SQL.
The EVLW is a further derivative of CO, MTt and DSt.
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